Additional file 7: of Association of EGLN1 genetic polymorphisms with SpO2 responses to acute hypobaric hypoxia in a Japanese cohort

Figure S5. Relationship between SpO2 and respiratory exchange ratio at 60 min (equivalent to 4000 m) for rs12097901 (a) and rs2790859 (b). Red characters represent highlander alleles. Blue line and gray band represent a regression line and its 95% confidence interval, respectively. Circle colors indicate genotypes of each SNP. The mean slope of the regression line was 0.002. Linear regression analysis showed no significant correlation (r2 = 0.012, P = 0.474). ANCOVA also showed no significant differences in the regression coefficient between genotypes (F(2, 40) = 0.19, P = 0.825 for rs12097901; F(2, 40) = 0.98, P = 0.384 for rs2790859) and in the adjusted mean values (F(2, 42) = 0.59, P = 0.557 for rs12097901; F(2, 42) = 0.17, P = 0.840 for rs2790859). (PDF 215 kb)