Electrochemical inferences from the ergodicity of the human granulocyte system

The measurements performed on human subjects by means of radioactive tracers prove the existence of an ergodic linear relationship, which relates the ratio (Co/Mo) of the granulocytes Co in the circulating pool divided by the marginated granulocytes Mo, versus the circulating granulocytes Co. A constraint among the parameters of the granulocyte system, which was previously anticipated on a pure electrochemical basis, is quantitatively evaluated. The ergodicity gives also a constant ratio between the limiting values of the granulocyte margination and demargination rates of different subjects. The latter result suggests that a new electrochemical constraint should exist which expresses the ratio between the maximum rates at which the margination and demargination processes may occur.