Correlation of serum vitamin D levels with serum levels of alkaline phosphatase

Objectives: To determine whether serum vitamin D levels are correlated with serum levels of alkaline phosphatase or not? Study Design: Case control cross sectional study. Setting: Gastroenterology unit of private teaching hospital in Peshawar. Period: From November 2015-Januaray 2016. Material and Methods: 100 participants meeting the criteria were included in the study. Fifty clinically normal young adults and fifty were non cirrhotic chronic hepatitis C patients were included in the study. Venous blood samples were taken from all the study participants and serum vitamin D levels were determined by Electro-chemiluminescence binding assay (ECLIA) and serum alkaline phosphatase was determined by Photometric Kinetics. Results: patients were divided into two groups on the basis of gender i.e.25 males and 25 females. A correlation between vitamin D and alkaline phosphatase was determined. Alkaline phosphatase was raised in the non cirrhotic chronic hepatitis C patients. Pearson correlation was applied to find out the relation between vitamin D levels and alkaline phosphatase in the two groups which had a significant relationship with a p-value of 0.01. A positive correlation between alkaline phosphatase and parathyroid hormone was found with a p value of