Distannoxane-Catalyzed Selective Acetylation of 3-Chloropropane-1,2-diol: A Convenient Synthesis of Enantiopure Epichlorohydrin

Authors :: Akihiro Orita
Yutaka Yasui
Junzo Otera
Toshihide Ito
Source :: Synlett. 1999:1927-1929
Publication Year :: 1999
Publisher :: Georg Thieme Verlag KG, 1999.
Abstract: A distannoxane catalyst effects exclusive acetylation of the primary alcohol of 3-chloropropane-1,2-diol. This reaction provides a convenient access to enantiopure epichlorohydrin.

Subjects :: inorganic chemicals
Chemistry
organic chemicals
Organic Chemistry
Diol
Primary alcohol
Catalysis
chemistry.chemical_compound
Enantiopure drug
Acetylation
polycyclic compounds
Organic chemistry
heterocyclic compounds
Epichlorohydrin

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