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A highly sensitive, single selective, fluorescent sensor for Al3+ detection and its application in living cell imaging
- Source :
- Journal of Luminescence. 155:180-184
- Publication Year :
- 2014
- Publisher :
- Elsevier BV, 2014.
-
Abstract
- A new o-aminophenol-based fluorogenic chemosensor methyl 3,5-bis((E)-(2-hydroxyphenylimino)methyl)-4-hydroxybenzoate 1 have been synthesized by Schiff base condensation of methyl 3,5-diformyl-4-hydroxybenzoate with o-aminophenol, which exhibits high selectivity and sensitivity toward Al3+. Fluorescence titration studies of receptors 1 with different metal cations in CH3OH medium showed highly selective and sensitive towards Al3+ ions even in the presence of other commonly coexisting metal ions. The detection limit of Al3+ ions is at the parts per billion level. Interestingly, the Al(III) complex of 1 offered a large Stokes shift (>120 nm), which can miximize the selfquenching effect. In addition, possible utilization of this receptor as bio-imaging fluorescent probe to detect Al3+ in human cervical HeLa cancer cell lines was also investigated by confocal fluorescence microscopy.
- Subjects :
- Detection limit
Schiff base
integumentary system
biology
Metal ions in aqueous solution
Biophysics
Analytical chemistry
General Chemistry
Condensed Matter Physics
Photochemistry
biology.organism_classification
Biochemistry
Fluorescence
Atomic and Molecular Physics, and Optics
HeLa
chemistry.chemical_compound
symbols.namesake
chemistry
Stokes shift
symbols
Fluorescence microscope
Titration
Subjects
Details
- ISSN :
- 00222313
- Volume :
- 155
- Database :
- OpenAIRE
- Journal :
- Journal of Luminescence
- Accession number :
- edsair.doi...........9557ebf2e1f8ef0e34c6c0a675508a2b