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A new general synthesis of N-mono-and N-di-substituted 2-aminothiazoles

Authors :
Michael D. Brown
G. Denis Meakins
Gordon H. Whitham
David W. Gillon
Source :
Journal of the Chemical Society, Chemical Communications. :444
Publication Year :
1982
Publisher :
Royal Society of Chemistry (RSC), 1982.

Abstract

Solutions of α-mercapto-ketone anions, generated from O-ethyl S-2-oxoethyl dithiocarbonates and piperidine, react with cyanamides to give 2-aminothiazoles with substituents on the heterocycle or the exo-nitrogen atom.

Subjects

Subjects :
chemistry.chemical_compound
chemistry
Stereochemistry
Molecular Medicine
Atom (order theory)
Piperidine
Medicinal chemistry

Details

ISSN :
00224936
Database :
OpenAIRE
Journal :
Journal of the Chemical Society, Chemical Communications
Accession number :
edsair.doi...........970d5da506300b0017f3b0d380550a92
Full Text :
https://doi.org/10.1039/c39820000444
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