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Four new highly oxidized sesquiterpene lactones from the leaves of Artemisia argyi

Authors :
Hua-Rong Zhao
Jian-Guang Luo
Xiao-Qin Liu
Ling-Yi Kong
Xiu-Tao Wu
Source :
Phytochemistry Letters. 43:173-178
Publication Year :
2021
Publisher :
Elsevier BV, 2021.

Abstract

Four new highly oxidized sesquiterpene lactones, Argyoxynolides A–D, along with two known analogs were isolated from the leaves of Artemisia argyi H.Lev. & Vaniot. Their structures were characterized utilizing extensive spectroscopic methods. All isolates were evaluated for the LPS-induced nitric oxide (NO) production inhibitory activity and one compound exhibited activity with IC50 = 37.95 ± 4.39 μM.

Details

ISSN :
18743900
Volume :
43
Database :
OpenAIRE
Journal :
Phytochemistry Letters
Accession number :
edsair.doi...........97789c15c9f1bccf9df6255ab2477545
Full Text :
https://doi.org/10.1016/j.phytol.2021.03.011