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High sensitivity enhancement of multi-shaped silver-nanoparticle-decorated hydrophilic PVDF-based SERS substrates using solvating pretreatment
- Source :
- Sensors and Actuators B: Chemical. 347:130614
- Publication Year :
- 2021
- Publisher :
- Elsevier BV, 2021.
-
Abstract
- We report an extremely sensitive and ultra-low-cost PVDF-based SERS substrate using an easy fabrication process that can be conducted in a laboratory and scaled up for industrial applications. Hydrophilic PVDF membranes were sequentially dipped in ethanol and aqueous sodium chloride solution, following which multi-shaped Ag nanoparticles were deposited on the surface of the membranes by suction filtration. The simple solvating pretreatment led to an approximately 188-fold enhancement in the SERS signal intensity of R6G. Using the hydrophilic PVDF-based SERS substrate, subnanomolar sensitivity for R6G was achieved using 3 μL of sample volume on a 3×3 mm2 SERS substrate within 1 min detection time and without the need for concentration or drying processes. To demonstrate the feasibility of the developed SERS substrate as a sensor for bacterial spore detection, it was applied for the detection of the representative biomarker dipicolinic acid (DPA). The limits of detection of DPA and Bacillus spores were measured as 1 ppm and 5×103 spores/mL, respectively. The optimized configuration of low substrate area and wet micro-analyte volume makes the PVDF-based SERS substrate a simple and low-cost tool for the trace-level detection of small molecules in a rapid, sensitive, and high-throughput manner.
- Subjects :
- Detection limit
Materials science
Aqueous solution
fungi
Metals and Alloys
Substrate (chemistry)
Condensed Matter Physics
Dipicolinic acid
Silver nanoparticle
Surfaces, Coatings and Films
Electronic, Optical and Magnetic Materials
law.invention
chemistry.chemical_compound
Membrane
chemistry
Chemical engineering
law
Materials Chemistry
Bacterial spore
Electrical and Electronic Engineering
Instrumentation
Filtration
Subjects
Details
- ISSN :
- 09254005
- Volume :
- 347
- Database :
- OpenAIRE
- Journal :
- Sensors and Actuators B: Chemical
- Accession number :
- edsair.doi...........97a387ded02e549fc2fb001d1456af80