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Development of a Blood-based Transcriptional Risk Score for Chronic Obstructive Pulmonary Disease

Authors :
Matthew Moll
Adel Boueiz
Auyon J. Ghosh
Aabida Saferali
Sool Lee
Zhonghui Xu
Jeong H. Yun
Brian D. Hobbs
Craig P. Hersh
Don D. Sin
Ruth Tal-Singer
Edwin K. Silverman
Michael H. Cho
Peter J. Castaldi
James D. Crapo
Barry J. Make
Elizabeth A. Regan
Terri Beaty
Ferdouse Begum
Michael Cho
Dawn L. DeMeo
Adel R. Boueiz
Marilyn G. Foreman
Eitan Halper-Stromberg
Lystra P. Hayden
Jacqueline Hetmanski
John E. Hokanson
Nan Laird
Christoph Lange
Sharon M. Lutz
Merry-Lynn McDonald
Margaret M. Parker
Dmitry Prokopenko
Dandi Qiao
Phuwanat Sakornsakolpat
Emily S. Wan
Juan Pablo Centeno
Jean-Paul Charbonnier
Harvey O. Coxson
Craig J. Galban
MeiLan K. Han
Eric A. Hoffman
Stephen Humphries
Francine L. Jacobson
Philip F. Judy
Ella A. Kazerooni
Alex Kluiber
David A. Lynch
Pietro Nardelli
John D. Newell
Aleena Notary
Andrea Oh
James C. Ross
Raul San Jose Estepar
Joyce Schroeder
Jered Sieren
Berend C. Stoel
Juerg Tschirren
Edwin Van Beek
Bram van Ginneken
Eva van Rikxoort
Gonzalo Vegas Sanchez-Ferrero
Lucas Veitel
George R. Washko
Carla G. Wilson
Robert Jensen
Douglas Everett
Jim Crooks
Katherine Pratte
Matt Strand
Gregory Kinney
Kendra A. Young
Surya P. Bhatt
Jessica Bon
Alejandro A. Diaz
Susan Murray
Xavier Soler
Russell P. Bowler
Katerina Kechris
Farnoush Banaei-Kashani
Source :
American Journal of Respiratory and Critical Care Medicine. 205:161-170
Publication Year :
2022
Publisher :
American Thoracic Society, 2022.

Abstract

Rationale: The ability of peripheral blood biomarkers to assess COPD risk and progression is unknown. Genetics and gene expression may capture important aspects of COPD-related biology that predict...

Details

ISSN :
15354970 and 1073449X
Volume :
205
Database :
OpenAIRE
Journal :
American Journal of Respiratory and Critical Care Medicine
Accession number :
edsair.doi...........97e212e59738bc6a7d7afd610ced65f5
Full Text :
https://doi.org/10.1164/rccm.202107-1584oc