Back to Search Start Over

A case of psoriasis vulgaris which produced various pigment freckles under psoriasis treatment including lentigo maligna

Authors :
Yumi Aoyama
Makoto Yanagihara
Akifumi Yamamoto
Shunji Mori
Kazufumi Yoneda
Mariko Seishima
Source :
Skin Cancer. 8:121-125
Publication Year :
1993
Publisher :
The Japanese Skin Cancer Society, 1993.

Abstract

A 44-year-old male had been suffered from psoriasis for 12 years. He had been treated with tar and topical steroid. In addition, he received PUVA and UVB therapy for 12 years since 1979. The total irradiated amount of UVA and UVB was 831 joules/cm2 and 102 joules/cm2, respectively. He had also taken etretinate in 1984 and methotrexate in 1987. When he was admitted to our hospital for the exacerbation of psoriasis, a lot of pigmented frecles were found. Forty-eight pigmented lesions could be classified into 5 different types; type A to E. Type A is lentigo simplex which shows an increased production of melanin. Type B is a lentigo simplex with atypical melanocytic hyperplasia. Type C shows a lentigo simplex with atypical melanocytic hyperplasia and remarkable pigment blockade. Type D is a junction nevus with nests of atypical melanocytes. Type E is a lentigo maligna with the nests of atypical spindle- shaped melanocytes that extents along epidermal-dermal junction. Type E pigmented lesions are distributed in intermittently sun-exposed skin. In this case, there were 2 nevus cell nevus, 12 type A, 20 type B, 5 type C, 5 type D, and 4 type E in 48 pigmented lesions. There was no correlation between the size and the type of pigmented lesions.

Details

ISSN :
18843549 and 09153535
Volume :
8
Database :
OpenAIRE
Journal :
Skin Cancer
Accession number :
edsair.doi...........98e276b510f9848d18c8fa248004c3f3
Full Text :
https://doi.org/10.5227/skincancer.8.121