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One-pot three-component reaction providing 1,5-benzodiazepine derivatives

Authors :
Kenichi Murai
Ryo Nakatani
Yasuyuki Kita
Hiromichi Fujioka
Source :
Tetrahedron. 64:11034-11040
Publication Year :
2008
Publisher :
Elsevier BV, 2008.

Abstract

The novel one-pot three-component reaction of aromatic aldehydes, 1,2-phenylenediamine, and β-keto esters is described. This reaction involves the γ-selective C–C bond formation of β-keto esters and produces 1,5-benzodiazepine derivatives.

Details

ISSN :
00404020
Volume :
64
Database :
OpenAIRE
Journal :
Tetrahedron
Accession number :
edsair.doi...........9bc42be9ccf0a806b7ae896ac11e0bf6
Full Text :
https://doi.org/10.1016/j.tet.2008.09.076