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Rescate con rituximab en paciente con liquen plano esofágico refractario

Authors :
Francisco Javier Jiménez Pérez
Juan Carrascosa Gil
Silvia Goñi Esarte
Juan José Vila Costas
María Luz Almendral López
David Ruiz-Clavijo García
Antonio Arin Letamendia
Source :
Gastroenterología y Hepatología. 36:264-267
Publication Year :
2013
Publisher :
Elsevier BV, 2013.

Abstract

Esophageal lichen planus (ELP) is a rare condition with unknown prevalence that can sometimes be underestimated due to the subtle and nonspecific findings of diagnostic workup. Oral lesions rarely extend to the esophageal mucosa, but when they do, the most frequent symptoms are dysphagia and odynophagia. There is often a significant delay in diagnosis and inadequate treatment. We report the case of a 59-year-old woman diagnosed with ELP, successfully treated with rituximab, a chimeric monoclonal antibody that depletes CD20+B cells. To our knowledge, this is only the second report of this treatment in ELP.

Details

ISSN :
02105705
Volume :
36
Database :
OpenAIRE
Journal :
Gastroenterología y Hepatología
Accession number :
edsair.doi...........9bf1b6fbda8e204da4026c136d4c8222