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ChemInform Abstract: PURINES. XXII. METHYLATION OF 1-, 3-, 7-, 9-, AND N6-METHYLADENINES BEARING A A METHOXYL GROUP AT THE N6-POSITION: A SYNTHESIS OF 7,9-DIMETHYLADENINE

Authors :
Tsuyoshi Nakasaka
Taisuke Itaya
Fumiko Tanaka
Kiyomi Yamamoto
Tohru Saito
Tozo Fujii
Kazuyo Mohri
Source :
Chemischer Informationsdienst. 15
Publication Year :
1984
Publisher :
Wiley, 1984.

Abstract

The effect of the N6-methoxy group on regioselectivity in methylation of all five possible isomers of N-methyladenine has been investigated. The methoxyl group attached to all these isomers orients methylation to a considerable extent to nitrogen(s) in the same pyrimidine or imidazole moiety that the original N-methyl group is attached to. On the basis of the results of the present methylation study, 7,9-dimethyladeninium perchlorate has been synthesized from 7- or 9-methyl-N6-methoxyadenine.

Details

ISSN :
00092975
Volume :
15
Database :
OpenAIRE
Journal :
Chemischer Informationsdienst
Accession number :
edsair.doi...........9c1eb03c2a0e026fb461bebc3d9b9df9
Full Text :
https://doi.org/10.1002/chin.198410192