Rh(II)-catalyzed intramolecular dearomatizing annulation of N-sulfonyl-1,2,3-triazoles: synthesis of polycyclic spiroindolines

An efficient approach for the synthesis of polycyclic spiroindolines has been developed by utilizing Rh(II)-catalyzed dearomatizing annulation of sulfonyl triazoles. An enantioselective variant of the process was also looked into briefly to achieve polycyclic spiroindolines in good yield with a promising 73.3: 26.7 enantiomeric ratio, demonstrating the potential for asymmetric catalysis.