CMOS Sensor Interface Arrays for DNA Detection

Sensor arrays for fully electronic DNA detection based on an extended CMOS process are discussed. An introduction to the used DNA detection method and to the modified CMOS process is given, and special emphasis is put on design issues of circuit blocks whose function is particularly related to the electrochemical operation principle of the chip. Stability and accuracy aspects are considered in detail. Measured data are shown from electrical characterizations as well as from biological experiments.