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Effects of Doxorubicin on Behavior of Rats and Distribution of NCAM in their Brain
- Source :
- Neurophysiology. 49:158-161
- Publication Year :
- 2017
- Publisher :
- Springer Science and Business Media LLC, 2017.
-
Abstract
- It was found that considerable structure-dependent changes in the distribution of neuronal cell adhesion molecules (NCAM) are observed in the brain of rats under conditions of doxorubicin-induced cardiomyopathy. This is accompanied by decreases in the intensity of locomotor and orientational/ research activity of the animals and changes in the stress-related indices in the “Open field” test.
- Subjects :
- 0301 basic medicine
Physiology
Chemistry
General Neuroscience
Cardiomyopathy
medicine.disease
Open field
Intensity (physics)
03 medical and health sciences
030104 developmental biology
nervous system
medicine
Biophysics
Distribution (pharmacology)
Doxorubicin
Neural cell adhesion molecule
sense organs
skin and connective tissue diseases
Neuronal Cell Adhesion Molecule
medicine.drug
Subjects
Details
- ISSN :
- 15739007 and 00902977
- Volume :
- 49
- Database :
- OpenAIRE
- Journal :
- Neurophysiology
- Accession number :
- edsair.doi...........9e3e47df14461efa8ac750bd9d691e79