TBAF-catalyzed cyclization of 6-hydroxyhex-2-ynoates and 7-hydroxyhept-2-ynoates

Authors :: Su Ping Liu
Ping Jing Jia
Wei Yu
Xiao Qing Wang
Source :: Chinese Chemical Letters. 22:931-934
Publication Year :: 2011
Publisher :: Elsevier BV, 2011.
Abstract: Tetrabutyl ammonium fluoride (TBAF) was found to be capable of catalyzing the intramolecular hydroalkoxylation of 6-hydroxyhex-2-ynoates and 7-hydroxyhept-2-ynoates. The reaction could be used to prepare 2,5-substituted THF rings and 2,6-substituted THP rings.

Subjects :: chemistry.chemical_compound
Chemistry
Intramolecular force
Organic chemistry
Ammonium fluoride
General Chemistry
Tetrahydropyran
Hydroalkoxylation
Tetrahydrofuran
Catalysis

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