An Analysis on the Influence that the Position and Number of Control Points Have on MLS Registration of Medical Images

In this paper an analysis on the influence that the selection of fiducial points has on the Moving Least Square registration of medical images has been presented. MLS is a point based method which needs selection of fiducial (control) points. Here the mapping is weighted by the distance of current pixel from the selected point. Hence it is deemed significance to investigate on the effect that the position and number of the selected control points have on registered image. The analysis is done by manually selecting the points from rigid and non-rigid regions, near and far off regions from the two images and by also varying the number of points. To assess the results comparison has been done with the TPS registration by computing the TRE.