Synthesis of macrobicyclic compounds containing aza-crown ether fragments and study of their complexation with zinc and cadmium nitrates

N-(3,5-Dibromobenzyl) derivatives of 1-aza-15-crown-5 and 1-aza-18-crown-6 were synthesized in high yields and their palladium-catalyzed amination reactions with various linear polyamines were studied. As a result, macrobicyclic compounds were obtained in yields up to 56%. The complexation of some macrocycles with zinc and cadmium nitrates was studied by NMR titration.