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ChemInform Abstract: Microwave-Assisted Three-Component Reactions Leading to Pyrano-Fused Pyrazolo[3,4-b]pyridines

Authors :
Bi-Hui Xu
Bo Jiang
Shu-Jiang Tu
Yin‐Ping Liu
Man-Su Tu
Xing-Hang Wang
Source :
ChemInform. 46
Publication Year :
2015
Publisher :
Wiley, 2015.

Abstract

A series of pyrano-fused pyrazolo[3,4-b]pyridine derivatives with an aryl group presenting the 2-position of the pyridine nucleus have been synthesized by microwave-assisted three-component reactions of aldehydes, tetrahydropyran-4-one, and 3-methyl-1-phenyl-1H-pyrazol-5-amine in HOAc. This method is very efficient because of short reaction times and easy work-up, and it provides an efficient and promising synthetic strategy for the construction of the tricyclic pyrano-fused pyrazolo[3,4-b]pyridine skeleton.

Details

ISSN :
09317597
Volume :
46
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........9fc11aa49ece7c5a47bd0ecc753524ff