Alcohol and psychoactive substances abuse in Brazil: A cross-sectional study

Conclusions: Individuals genetically predisposed to dependence exhibit an altered stress response to administration of an opioid drug, possibly due to a lack of HPA axis activation. These subjects may be more likely to self administer drugs when coping with stressful situations. These results will be compared with a non-drug control group. Financial support: This research was supported by an Australian Postgraduate Award.