Centile-based ultrasound morphometric tables

Current ultrasound morphometric tables estimate centiles assuming normal distribution and similar variation throughout gestation. Our goal was to develop normative tables for biparietal diameter, femur length and average abdominal diameter using actual centiles. We studied the last complete ultrasound examination from 9510 singleton, live pregnancies without major malformations delivered at our hospital. Actual 5th, 10th, 50th, 90th and 95th centiles were calculated for each week and compared to estimates based on means and standard deviations. With advancing gestational age, variation in average abdominal diameter increased and variation in biparietal diameter and femur length remained stable. The largest difference between an actual and an estimated centile limit was 2 mm for biparietal diameter or femur length and 3 mm for average abdominal diameter. Differences between true and estimated centile limits were less than the intraobserver variation of the ultrasound measurements and therefore clinically unimportant. Copyright © 1995 International Society of Ultrasound in Obstetrics and Gynecology