ent-(8S,10R)-15,16-Epoxy-19-norcleroda-4,11,13(16),14-tetraene-18,6(R):20,12-diolactone (isocrotocaudin)

The title compound, C19H18O5, is a diastereoisomer of crotocaudin, both being isolated from the plants of genus Croton. In isocrotocaudin, the furan moiety makes a dihedral angle with the adjacent lactone of 13.53 (17)°. The cyclo­hexyl ring of the diterpene moiety adopts a chair confirmation. The weak intermolecular C—H⋯O hydrogen bonds link the mol­ecules into linear chains along the c axis.