Additional file 7: Figure S2. of Stringent comparative sequence analysis reveals SOX10 as a putative inhibitor of glial cell differentiation

SOX8 and SOX9 also increase the regulatory activity of SOX10-CCS-13, SOX10-CCS-19, and SOX10-CCS-51. Luciferase reporter gene constructs harboring SOX10-CCS-13, SOX10-CCS-19, or SOX10-CCS-51 were transfected into mouse motor neurons (MN1) with constructs to express SOX8 or SOX9. The luciferase activity associated with each construct in the presence of SOX8 or SOX9 is expressed relative to that of the same construct in the absence of these transcription factors. Error bars indicate standard deviations. Please note that the SOX10 data are identical to those in Fig. 3a and are included to facilitate a comparison. (PDF 330 kb)