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Asiatic acid from Cyclocarya paliurus regulates the autophagy–lysosome system via directly inhibiting TGF-β type I receptor and ameliorates diabetic nephropathy fibrosis
- Source :
- Food & Function. 13:5536-5546
- Publication Year :
- 2022
- Publisher :
- Royal Society of Chemistry (RSC), 2022.
-
Abstract
- AA could decrease TGF-β1 secretion and suppress tubulointerstitial fibrosis by directly inhibiting TGF-βR1 and activate the autophagy–lysosome system in DN fibrosis.
- Subjects :
- General Medicine
Food Science
Subjects
Details
- ISSN :
- 2042650X and 20426496
- Volume :
- 13
- Database :
- OpenAIRE
- Journal :
- Food & Function
- Accession number :
- edsair.doi...........a23637024b13ec8badbf03e27d262735