Formulation development, optimization, and in vitro assessment of thermoresponsive ophthalmic pluronic F127-chitosan in situ tacrolimus gel

Authors :: Mohammad
Meenakshi Bhatia
Deepika Modi
Gaurav Kumar Jain
Prashant Kesharwani
Vaidehi Garg
Musarrat Husain Warsi
Source :: Journal of Biomaterials Science, Polymer Edition. 32:1678-1702
Publication Year :: 2021
Publisher :: Informa UK Limited, 2021.
Abstract: To overcome problems associated with topical delivery of tacrolimus (TCS), a thermoresponsive in situ gel system containing pluronic F127 (PL), and chitosan (CS) was developed, to enhance the preco...

Subjects :: In situ
Chromatography
Chemistry
0206 medical engineering
Biomedical Engineering
Biophysics
Bioengineering
02 engineering and technology
Poloxamer
021001 nanoscience & nanotechnology
020601 biomedical engineering
Tacrolimus
In vitro
Biomaterials
Chitosan
chemistry.chemical_compound
0210 nano-technology

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