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A Chiron Approach to (-)-Tetrahydrolipstatin

Authors :
Jhillu S. Yadav
A. R. Prasad
K. Vishweshwar Rao
Source :
Synthesis. 2006:3888-3894
Publication Year :
2006
Publisher :
Georg Thieme Verlag KG, 2006.

Abstract

An efficient chiron approach to the total synthesis of (-)-tetrahydrolipstatin is described. The main features of the synthetic strategy, which starts from tri-O-acetyl-D-glucal, are coppermediated C-C bond formation, Frater alkylation, and Barton-McCombie deoxygenation.

Details

ISSN :
1437210X and 00397881
Volume :
2006
Database :
OpenAIRE
Journal :
Synthesis
Accession number :
edsair.doi...........a285b0676c18cd28b4f65d5beafca3fa