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Metal-Free trans -Aziridination of Zerumbone: Synthesis and Biological Evaluation of Aziridine Derivatives of Zerumbone
- Source :
- European Journal of Organic Chemistry. 2017:3072-3077
- Publication Year :
- 2017
- Publisher :
- Wiley, 2017.
-
Abstract
- Herein, we describe a metal-free, iodosobenzenediacetate mediated trans-aziridination of zerumbone by the direct use of sulphonamides. The preliminary in vitro-screening showed better anti-proliferative and anti-diabetic activity compared to parent compound zerumbone.
Details
- ISSN :
- 1434193X
- Volume :
- 2017
- Database :
- OpenAIRE
- Journal :
- European Journal of Organic Chemistry
- Accession number :
- edsair.doi...........a2e8e090dd16f572e21ff87f4e4327da
- Full Text :
- https://doi.org/10.1002/ejoc.201700410