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Mechanical Properties of Primary and Immortal Fibroblasts in Cell Bi-Layers
- Source :
- ASME 2012 Summer Bioengineering Conference, Parts A and B.
- Publication Year :
- 2012
- Publisher :
- American Society of Mechanical Engineers, 2012.
-
Abstract
- Immortalized cells are commonly used as analogs for primary cells in many cell mechanics, tissue engineering, and biochemical assays. However, it is not well-established whether immortal cell lines can mimic the behavior of primary cells in more physiological (three-dimensional) environments. For this project, we investigate the mechanical properties of primary cardiac fibroblasts (CFs) and 3T3 transformed fibroblasts when cultured in cell bi-layers by comparing the cells’ viscoelastic properties.Copyright © 2012 by ASME
Details
- Database :
- OpenAIRE
- Journal :
- ASME 2012 Summer Bioengineering Conference, Parts A and B
- Accession number :
- edsair.doi...........a4898f428678bd2b230407b5668306c2
- Full Text :
- https://doi.org/10.1115/sbc2012-80385