Posteroanterior Cephalometric Analysis of the Parental Craniofacial Morphology in Orofacial Clefting

Objective: To evaluate the parental craniofacial morphology in orofacial clefting (OFC). Design: Case-control posteroanterior cephalometric study. Setting: The Department of Orthodontics, University of Dundee Dental School, Scotland, United Kingdom. Participants: Ninety-two parents from a completely ascertained sample of 286 Scottish babies with nonsyndromic OFC and 43 comparison group volunteers from the University of Dundee Dental School. Main Outcome Measures: A conventional cephalometric analysis was used to measure linear distances and their ratios, angles, and areas. Two-sample Student's t tests and a discriminant analysis were applied to the data, and the clinically important statistically significant variables were identified using an accepted protocol. Results: Sixty-four linear distances, 10 ratios, 52 angles, and 7 areas statistically significantly differed between the parental and comparison groups (p < .01). Of these, 62 linear distances (22%), 9 ratios (45%), 41 angles (41%), and 6 ...