Catalytic asymmetric synthesis of N-substituted tetrahydroquinoxalines via regioselective Heyns rearrangement and stereoselective transfer hydrogenation in one pot

Authors :: Zhuo Tang
Guangxun Li
Xin Cui
Gao-feng Yang
Jinzhong Zhao
Xiao-kang Nie
Ding-qiang Fu
Jin Huang
Source :: Chemical Science. 12:4789-4793
Publication Year :: 2021
Publisher :: Royal Society of Chemistry (RSC), 2021.
Abstract: N-Substituted tetrahydroquinoxalines (37 examples) were step-economically obtained in good yield (

Subjects :: Reaction mechanism
Chemistry
Yield (chemistry)
Enantioselective synthesis
Regioselectivity
Substrate (chemistry)
Stereoselectivity
General Chemistry
Transfer hydrogenation
Medicinal chemistry
Catalysis

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