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FOLLICULAR MUCINOSIS IN A PATIENT WITH PARAPSORIASIS

Authors :
Raluca Gabriela Miulescu
Mihai Cristian Dumitrascu
Ana Maria Alexandra Stănescu
Adelina Popa
Carmen Cristina Draghici
Florica Sandru
Source :
Romanian Journal of Clinical Research. 2
Publication Year :
2019
Publisher :
Asociatia Cercul de Stiinte Chirurgicale, 2019.

Abstract

We present the case of a young patient, without comorbidities, who developed an erythematous-squamous, disseminated, discrete itchy rash, associated with scarring alopecia at the level of the scalp and the external third of the eyebrows, in 3-year evolution, in which two skin biopsies showed: subacute spongiotic dermatitis and psoriasiform dermatitis. As new lesions continued to appear despite treatment with phototherapy, systemic, local corticosteroids, it was decided to perform another skin biopsy: loose areas, granular appearance that color blue with Alcian Blue staining, thus supporting the diagnosis of follicular mucinosis. The treatment consisted of Acitretin 30 mg / day, with favorable evolution. Follicular mucinosis is a rare inflammatory disease, characterized by mucin deposits located in the follicular epithelium and sebaceous glands. There are two clinical forms: a primary, benign, limited to the skin, and a secondary form, commonly associated with cutaneous T-cell lymphoma. The evolution of both forms of follicular mucinosis is a chronic one, and the correct therapeutic attitude consists primarily in the periodic surveillance of the patient, with possible repeat biopsy, to exclude the form associated with a mycosis fungoides. The management of such patients is extremely difficult, as a number of conditions must be evaluated, such as: screening for collagenosis, diabetes, inflammatory bowel disease, evaluation of thyroid function, tumor markers.

Details

ISSN :
26020467
Volume :
2
Database :
OpenAIRE
Journal :
Romanian Journal of Clinical Research
Accession number :
edsair.doi...........aa1609e6b684e5e89e94c7276d918a6d