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Effect of Audible Sound on Protein Crystallization
- Source :
- Crystal Growth & Design. 16:705-713
- Publication Year :
- 2016
- Publisher :
- American Chemical Society (ACS), 2016.
-
Abstract
- The successful crystallization of proteins is important because their molecular three-dimensional structures can be obtained through X-ray diffraction when in their crystalline form. Investigation of the crystallization process is beneficial for this purpose. We have reported that protein crystallization is sensitive to audible sound, which is commonly present but is often ignored. Here we investigate the effect of audible sound parameters, especially frequency, on a protein crystallization. We show a significant facilitation of protein crystallization using 5000 Hz audible sound, possible mechanism was also tried to be clarified. Suitably controlled audible sound can be beneficial for promoting protein crystallization. Therefore, audible sound can be used as a simple tool to promote protein crystallization. In addition, the processing of other types of materials may also be affected by audible sound.
- Subjects :
- 0301 basic medicine
Sound (medical instrument)
Materials science
Acoustics
A protein
02 engineering and technology
General Chemistry
021001 nanoscience & nanotechnology
Condensed Matter Physics
law.invention
03 medical and health sciences
030104 developmental biology
law
otorhinolaryngologic diseases
General Materials Science
Crystallization
0210 nano-technology
Protein crystallization
Subjects
Details
- ISSN :
- 15287505 and 15287483
- Volume :
- 16
- Database :
- OpenAIRE
- Journal :
- Crystal Growth & Design
- Accession number :
- edsair.doi...........ac3b2a8264fab9bef64dde6a99ddb821