A prolonged activated partial thromboplastin time revealing a childhood systemic lupus erythematosus

Childhood-onset systemic lupus erythematosus (cSLE) is a rare multisystem autoimmune disease characterized by inflammatory and autoimmune reaction in several organs. The diagnosis can be difficult due to the heterogeneity of clinical manifestations. Early diagnosis can lead to a proper diagnosis and treatment to control inflammation and to avoid life-threatening complications.