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Cardiac proton spectroscopy using large coil arrays
- Source :
- NMR in Biomedicine. 26:276-284
- Publication Year :
- 2012
- Publisher :
- Wiley, 2012.
-
Abstract
- Large coil arrays are widely used in clinical routine for cardiovascular imaging providing extended spatial coverage and enabling accelerated acquisition using parallel imaging approaches. This work investigates the use of large coil arrays in single-voxel cardiac spectroscopy for the detection of myocardial creatine and triglyceride content. For this purpose, a navigator-gated and cardiac-triggered point-resolved spectroscopy sequence was implemented, and data obtained in 11 healthy volunteers using 32- and 5-element coil arrays were compared. For combination of the individual coil element signals, four strategies were evaluated differing in the manner of estimation of the complex coil weights and the amount of additional information required for coil combination. In all volunteers, and with both the 32- and 5-channel coil arrays, triglyceride-to-water (0.44 ± 0.19% and 0.45 ± 0.17%) and total creatine-to-water (0.05 ± 0.02% and 0.05 ± 0.01%) contents were computed. The values were found to agree well, showing an intraclass correlation coefficient of 0.76 (p
- Subjects :
- Materials science
Proton
Intraclass correlation
Clinical routine
030218 nuclear medicine & medical imaging
03 medical and health sciences
Triglyceride content
0302 clinical medicine
Nuclear magnetic resonance
Signal-to-noise ratio (imaging)
Electromagnetic coil
Molecular Medicine
Radiology, Nuclear Medicine and imaging
Parallel imaging
Spectroscopy
030217 neurology & neurosurgery
Subjects
Details
- ISSN :
- 09523480
- Volume :
- 26
- Database :
- OpenAIRE
- Journal :
- NMR in Biomedicine
- Accession number :
- edsair.doi...........ae5d0c54f90e466071790c17c8c7a533