Lactate in the foetal brain: detection and implications

Background and methods: In six hydrocephalic foetuses (gestational age 29–38 wk), proton MR spectroscopy (1H-MRS) was performed in the basal ganglia for detection of lactate in vivo. Results: Lactate was present in two foetal brains, absent in two and not detectable because of movement in two. Conclusion: With adequate immobilization of the foetus, 1H-MRS can be used for detection of foetal brain lactate.