Back to Search Start Over

Technological Profile of Lipases in the Pharmaceutical Industry

Authors :
Flavia Maria Lins Mendes
Adelaide Maria de Souza Antunes
Gabrielle Barbosa Pinto
Source :
Mini-Reviews in Organic Chemistry. 17:701-716
Publication Year :
2020
Publisher :
Bentham Science Publishers Ltd., 2020.

Abstract

In recent decades, enzymes have been the target of considerable research, development, and innovation. This paper presents an up-to-date overview of the technological application of lipases in the pharmaceutical industry. Lipases have been used in a variety of ways in the pharmaceutical industry, both for obtaining bioactive molecules to overcome limitations in the formulation of medicines and in drug design. This is possible from alternative technologies, such as immobilization and the use of non-aqueous solvents that allow the use of lipases in commercial-scale processes. In addition, other technologies have provided the emergence of differentiated and more specific lipases in order to meet the perspectives of industrial processes. The research indicates that the following years should be promising for the application of lipase in the industrial biocatalysis and in drug design.

Details

ISSN :
1570193X
Volume :
17
Database :
OpenAIRE
Journal :
Mini-Reviews in Organic Chemistry
Accession number :
edsair.doi...........b23f4fe8b923c35d26e618c868eaedaa
Full Text :
https://doi.org/10.2174/1570193x16666190913181530