Effects of meals with different glycaemic index on postprandial blood glucose response in patients with Type 1 diabetes treated with continuous subcutaneous insulin infusion

Diabet. Med. 28, 227–229 (2011) Abstract Objective To evaluate the impact of high-glycaemic index and low-glycaemic index meals on postprandial blood glucose in patients with Type 1 diabetes treated with continuous subcutaneous insulin infusion. Methods Sixteen patients with Type 1 diabetes under continuous subcutaneous insulin infusion treatment, age 36 ± 0.5 years (mean ± sem), HbA1c 7.6 ± 0.2% (56 ± 1.1 mmol/mol), consumed two test meals with an identical macronutrient composition, but with a different glycaemic index: 59 vs. 90. Blood glucose was checked before the test meal and every 30 min thereafter for 180 min. The same preprandial insulin dose was administered on the two occasions. Results Blood glucose concentrations following the low-glycaemic index meal were significantly lower than those of the high-glycaemic index meal (P