Detection of EGFR Protein Using Terahertz Metamaterial Biosensor

Increasing the detection specificity and sensitivity of the epidermal growth factor receptor (EGFR) will benefit the diagnosis of a number of cancers. Terahertz metamaterial biosensors are very sensitive and able to detect trace biomolecules. In this work, we fabricated a bow-tie THz metamaterial biosensor and functionalized it with EGFR antibody for specific EGFR detection. The results demonstrate that the proposed strategy can achieve EGFR detection with high specificity and sensitivity. This has the potential to be introduced into clinical use for the fast diagnosis of EGFR related diseases.