Fractionated irradiation can induce functionally relevant multidrug resistance gene and protein expression in human tumor cell lines

Authors :: A. M. Asemissen
Ulrich Keilholz
Dirk Bottke
Thomas Wiegel
Wolfgang Hinkelbein
K. Heufelder
Source :: Journal of Clinical Oncology. 23:9573-9573
Publication Year :: 2005
Publisher :: American Society of Clinical Oncology (ASCO), 2005.
Abstract: 9573 Background: Radiotherapy (RT) can induce the expression of P-glycoprotein (gene product of the multidrug resistance [MDR] gene 1), which can lead to a broad cytostatic drug resistance. The kin...

Subjects :: Cancer Research
medicine.medical_treatment
fungi
food and beverages
Drug resistance
Biology
Molecular biology
Multidrug Resistance Gene
Protein expression
Radiation therapy
Gene product
Multiple drug resistance
Oncology
Cell culture
medicine
Gene

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