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ChemInform Abstract: Potent and Selective Cyclohexyl-Derived Imidazopyrazine Insulin-Like Growth Factor 1 Receptor Inhibitors with in vivo Efficacy
- Source :
- ChemInform. 42
- Publication Year :
- 2011
- Publisher :
- Wiley, 2011.
-
Abstract
- A series of 8-amino-imidazo[1,5-a]pyrazine derived inhibitors of IGF-1R which feature a substituted quinoline moiety at the C1 position and a cyclohexyl linking moiety at the C-3 position is synthesized.
Details
- ISSN :
- 09317597
- Volume :
- 42
- Database :
- OpenAIRE
- Journal :
- ChemInform
- Accession number :
- edsair.doi...........b54eab5be2b3c4f8725618a48e4f08cd