SEX STEROIDS INFLUENCE ON URIC ACID BINDING TO HUMAN PLASMA PROTEINS: 136

Uric acid binding to human plasma proteins has been studied in various physiological and paraphysiological conditions,including the following groups: I-a group of children aged 4-10 years; 2-a group of healthy males; 3-a group of subjects treated with estrogen preparations for prostatic cancer; 4-a group of regularly menstruating females with normal cycle; 5-a group of post-menopausal females; 6-a group of pregnant females; 7-a group of females treated with oral contraceptives; 8-a group of females treated with estrogen preparations for post menopausal symptoms. The results obtained demonstrate a significant correlation between the increase of plasma estrogen and the increase of the uric acid binding to human plasma proteins.