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The protection of luteolin against diabetic cardiomyopathy in rats is related to reversing JNK-suppressed autophagy

Authors :
Chi Xiao
Meng-Yuan Chen
Yu-Peng Han
Li-Juan Liu
Jia-Lin Yan
Ling-Bo Qian
Source :
Food & Function. 14:2740-2749
Publication Year :
2023
Publisher :
Royal Society of Chemistry (RSC), 2023.

Abstract

Luteolin improves cardiac function and myocardial remodeling with down-regulation of JNK/c-Jun/miR-221 pathway-inhibited autophagy in the diabetic heart, suggesting that luteolin's inhibition of DCM is associated with reversing JNK-suppressed autophagy.

Subjects

Subjects :
General Medicine
Food Science

Details

ISSN :
2042650X and 20426496
Volume :
14
Database :
OpenAIRE
Journal :
Food & Function
Accession number :
edsair.doi...........b61f92bf866350e5f687b3d6470f4246