Three New Triterpenoid Saponins from Ardisia crenata

Three new triterpenoid saponins, ardisicrenoside I (1), ardisicrenoside J (2), and ardisicrenoside M (3), along with eight known compounds, were isolated from the roots of Ardisia crenataSims. Their structures were elucidated as 16α-hydroxy-30,30-dimethoxy-3β-O-{β-D-xylopyranosyl-(12)-β-D-glucopyranosyl-(14)-[β-D-glucopyranosyl-(12)]-α-L-arabinopyranosyl}-13β,28-epoxyoleanane (1), 16α-hydroxy-30,30-dimethoxy-3β-O-{α-L-rhamnopyranosyl-(12)-β-D-glucopyranosyl-(14)-[β-D-glucopyranosyl-(12)]-α-L-arabinopyranosyl}-13β,28-epoxyoleanane (2), 30,30-dimethoxy-16-oxo-3β-O-{β-D-xylopyranosyl-(12)-β-D-glucopyranosyl-(14)-[β-D-glucopyranosyl-(12)]-α-L-arabinopyranosyl}-13β,28-epoxyoleanane (3), ardisiacrispin A (4), ardisiacrispin B (5), ardisicrenoside B (6), ardisicrenoside A (7), ardisicrenoside H (8), ardisicrenoside G (9), cyclamiretin A-3β-O-β-D-xylopyranosyl-(12)-β-D-glucopyranosyl-(14)-α-L-arabinopyranoside (10), and cyclamiretin A-3β-O-α-L-rhamnopyranosyl-(12)-β-D-glucopyranosyl-(14)-α-L-arabinopyranoside (11) by means of chemical and spectral analysis, and their cytotoxicities were evaluated in vitro.