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One-Time Intravitreal Injection of KVD001, a Plasma Kallikrein Inhibitor, in Patients with Central-Involved Diabetic Macular Edema and Reduced Vision

Authors :
John A. Wells
Andreas Maetzel
Lloyd Paul Aiello
David S. Boyer
Robert Tansley
Helen Hernandez
Victor H. Gonzalez
Edward P. Feener
Jennifer K. Sun
Raj K. Maturi
Source :
Ophthalmology Retina. 3:1107-1109
Publication Year :
2019
Publisher :
Elsevier BV, 2019.

Abstract

Safety of the intravitreal plasma kallikrein inhibitor (KVD001) was tested in patients with diabetic macular edema. KVD001 was well tolerated. Systemic absorption was low. Improvement of retinal edema and vision occurred in most study eyes.

Details

ISSN :
24686530
Volume :
3
Database :
OpenAIRE
Journal :
Ophthalmology Retina
Accession number :
edsair.doi...........bc6555ac14ddc25366b0c0a0ebb800ad
Full Text :
https://doi.org/10.1016/j.oret.2019.07.006