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Total synthesis of the indole alkaloid (±)-tacamonine

Authors :
David Din Belle
Mauri Lounasmaa
Arto Tolvanen
Source :
Tetrahedron Letters. 36:7141-7144
Publication Year :
1995
Publisher :
Elsevier BV, 1995.

Abstract

A simple and efficient method is described for the preparation of tacamonine (1) from the easily accessible ester 3. The method is based on the stereoselective synthesis of 20-epitacamonine (7), which is transformed to 1 using the Polonovski-Potier reaction.

Details

ISSN :
00404039
Volume :
36
Database :
OpenAIRE
Journal :
Tetrahedron Letters
Accession number :
edsair.doi...........bd4d20aa403a09773ee7ebf30cf8a853
Full Text :
https://doi.org/10.1016/0040-4039(95)01419-i