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A very potent factor V inhibitor interferes with the levels of all coagulation factors and causes a fatal hemorrhagic syndrome

A very potent factor V inhibitor interferes with the levels of all coagulation factors and causes a fatal hemorrhagic syndrome

Authors :
Hélène Kerspern
Sara Robin
Clelia Mornet
Claire Hoffmann
Jean Amiral
Fanny Mingant
Jean-Christophe Ianotto
Schéhérazade Rezig
Eric Lippert
Brigitte Pan Petesch
Hubert Galinat
Adam Collins
Hélène Jantzem
Source :
European Journal of Haematology. 103:137-139
Publication Year :
2019
Publisher :
Wiley, 2019.

Abstract

We report a very high factor V inhibitor affecting the measurement of all coagulation factors besides fibrinogen, all these factors being dramatically decreased. This inhibitor could be linked to antibiotic use. The patient died of massive hemorrhage before a plasma exchange could be initiated.

Details

ISSN :
16000609 and 09024441
Volume :
103
Database :
OpenAIRE
Journal :
European Journal of Haematology
Accession number :
edsair.doi...........be31ef5575a572c0c1915afcf6f2400d
Full Text :
https://doi.org/10.1111/ejh.13249