Assessment of a Possibility to Differentiate the Tumor Histological Type and Localization in Patients with Lung Cancer by the Composition of Exhaled Air

In clinical practice, exhaled air analysis is a promising approach for diagnosing lung cancer due to a possibility of rapid and noninvasive sampling. We analyzed the exhaled air of 80 patients with lung cancer to identify differences in the profiles of volatile organic compounds in patients with different histological types and localization of cancer using gas chromatography–mass spectrometry. Some volatile organic compounds and their ratios have been identified, statistically signficant differences in concentrations of which have been found in samples with different localization and histological type.