An integrated strategy for extraction and pre-concentration of four astragalosides from Radix Astragali by a formulated surfactant aqueous system

Integrated and environmentally friendly methods for extraction and enrichment of natural products have gained increasing interests. The proposed preparation process provides the possibility that extraction and pre-concentration for astragalosides from Radix Astragali roots can be conducted with the surfactant aqueous system in one single procedure. The formulated surfactant system composing of 2% TX-114 as surfactant and 0.03% (w/v) of Gemini 16-5-16 as co-surfactant showed higher extraction efficiency with ultrasonic-assisted method and four astragalosides could be enriched by the cloud point phenomenon of surfactant. This work represents a valuable alternative for the eco-friendly extraction and enrichment of secondary metabolites from plants.