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Total Synthesis of Aigialomycin D

Authors :
Samuel J. Danishefsky
Xudong Geng
Source :
ChemInform. 35
Publication Year :
2004
Publisher :
Wiley, 2004.

Abstract

The first total synthesis of resorcinylic macrolide aigialomycin D was described. The resorcinylic moiety was constructed by a highly efficient Diels−Alder reaction using a disiloxydiene and a 14-membered “ynolide” as the dienophile synthesized by ring-forming olefin metathesis.

Details

ISSN :
15222667 and 09317597
Volume :
35
Database :
OpenAIRE
Journal :
ChemInform
Accession number :
edsair.doi...........c0260f00e29886f1cc55814767b7c977